Amaryl Glimepiride. buy Amaryl online, buy Amaryl usa, buy Amaryl canada. 

Glimepiride is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications. Amaryl Glimepiride. buy amaryl online

Amaryl Glimepiride. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. buy amaryl online. 

Indications

Glimepiride is indicated in following conditions-

Glimepiride is indicated as an adjunct to diet and exercise to lower the blood glucose in patients with noninsulin dependent (Type II) diabetes mellitus (NIDDM) whose hyperglycemia cannot be controlled by diet and exercise alone.

Glimepiride may be used concomitantly with metformin when diet, exercise, and Glimepiride or metformin alone does not result in adequate glycaemic control.

Glimepiride is also indicated for use in combination with insulin to lower blood glucose in patients whose hyperglycaemia cannot be controlled by diet and exercise in conjunction with an oral hypoglycaemic agent. Amaryl Glimepiride

Pharmacology

Glimepiride is a sulfonylurea antidiabetic agent which decreases blood glucose concentration. The primary mechanism of action of Glimepiride appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells.

Dosage

In principle, the dosage of Glimepiride is governed by the desired blood sugar level. The dosage of Glimepiride must be the lowest which is sufficient to achieve the desired metabolic control.

Initial dose and dose titration: the usual initial dose is 1 mg once daily, if necessary, the daily dose can be increased. Any increase can be based on regular blood sugar monitoring, and should be gradual, i.e., at intervals of 1 to 2 weeks, and carried out stepwise, as follows: 1 mg -> 2 mg -> 3 mg -> 4 mg -> 6 mg.

Dose in patients with well controlled diabetes: the usual dose range in patients with well controlled diabetes is 1 to 4 mg daily. amaryl Gliclazide

Distribution of doses: Timing and distribution of doses are decided by the physician, in consideration of the patient’s current lifestyle. Normally, a single daily dose is sufficient. This should be taken immediately before a substantial breakfast or if none is taken immediately before the first main meal. It is very important not to skip meals after taking the drug. Amaryl Glimepiride

Secondary dosage adjustment: As control of diabetes improves, sensitivity to insulin increases; therefore, Glimepiride requirement may fall as treatment proceeds. To avoid hypoglycemia, timely dose reduction or cessation of Glimepiride therapy must be considered. A dose adjustment must also be

Administration

Glimepiride tablet must be swallowed with enough liquid. amaryl Gliclazide

Interaction

Based on experience with Glimepiride and known interactions for other sulfonylureas, the following interactions must be considered. Amaryl Glimepiride

In addition to insulin and other oral antidiabetic agents, drugs which may potentiate the hypoglycaemic action of Glimepiride include: ACE inhibitors, aminosalicylic acid, anabolic steroids and male sex hormones, azapropazone, chloramphenicol, ciofibrate, coumarin buy amaryl online

Contraindications

Glimepiride is not suitable for the treatment of insulin dependent (type I) diabetes mellitus, or for the treatment of diabetic ketoacidosis, nor for the treatment of diabetic coma. amaryl Gliclazide

Glimepiride must not be used in patients hypersensitive to Glimepiride, other sulfonylureas, other sulfonamides, severe hepatic dysfunction, severe impairment of renal function and dialysis patients. buy amaryl online

Side Effects

Hypoglycemia, temporary visual impairment, nausea, vomiting, diarrhea, abdominal pain, urticaria, fall in blood pressure.

Pregnancy & Lactation

Glimepiride must not be taken during pregnancy; a changeover to insulin is necessary. Patients planning a pregnancy must inform their physician and should change over to insulin. Ingestion of Glimepiride with breast milk feeding may harm the child. buy amaryl online Amaryl Glimepiride

Precautions & Warnings

in the initial weeks of treatment, the risk of hypoglycemia may be increased and necessitates careful monitoring. If such risk present it may be necessary to adjust the dosage of Glimepiride, Hypoglycaemia can almost be promptly controlled by immediate intake of carbohydrates (glucose or sugar).

Overdose Effects

Overdosage of sulfonylureas, including Glimepiride, can produce hypoglycaemia. Mild hypoglycaemic symptoms without loss of consciousness or neurologic findings should be treated aggressively with oral glucose and adjustments in drug dosage or meal patterns. buy amaryl online

Therapeutic Class

Sulfonylureas

Storage Conditions

Do not store above 30°C. Keep away from light and out of the reach of children.